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Preventive Medicine Associates, PLLC

MARCH 2022 TABLEHOPPING ARTICLE

A big topic amongst many people concerned with longevity and “health gevity” is the use of supplements. I’m not talking about Vitamin D or fish oil. I am talking about more controversial supplements like NR, NMN, and Fisetin. Will these supplements prolong your life and increase your health or will they cause cancer and wreck your metabolism?

We are talking about medications / supplements that affect metabolic pathways of aging including mTOR, but work primarily by affecting the Sirtuin Pathway. This pathway was discovered in the 1970’s and is a major anti-aging force. Aging is not just a date on a calendar …it’s a progressive loss of certain nutrients and an accumulation of certain toxins that ultimately affect basic cellular function including the mitochondria…the powerhouses of your cells.

Let’s start with the basic Niacin or B3. This water soluble vitamin is the backbone of one of the most basic and necessary energy molecules ..NADH that is only second to ATP as an energy store in the body. You can make niacin from the amino acid tryptophan but you can also get it from leafy veggies , liver, most meats, etc. There are several steps in between Niacin and NADH including a compound called Nicotinamide riboside which has been commercially available as a product since 2014. This , in turn, is turned into nicotinamide mononucleotide also called NMN. Two of these NMN molecules make up one unit of NAD which can now act as a hydrogen transporter / energy generator. We know that when we supplement yeast and mice with these agents they are healthier and live longer than unsupplemented animals. What about humans? Well we just don’t have enough answers for me to recommend any of these supplements except Niacin which I recommend people get as a B Complex or B Complete . Dr David Sinclair at Harvard is currently experimenting with all these compounds as well as Resveratrol and other senolytic molecules like ficiden and quercetin which may improve health and extend lifespan..quercetin reduces fatty liver and other markers of poor health/ inflammation. …ficiden is a plant molecule found in grapes, apples and is available as a supplement. Resveratrol also activates the sirtuin pathway but you would need to drink more than a hundred bottles of red wine a day but you can get 250 mg as a daily supplement which should be taken with some olive oil or other fat to improve absorption.

There are clinics in Florida and California where people are going for injections of NAD which they claim helps with depression, addiction and hangovers.

Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC

Now there are other classes of drugs that have promise. The drug rapamycin and its analogs have shown benefit of extending life span in every species studied so far it acts to inhibit mTOR it mimics fasting and mimics the effects of a low protein diet.This drug is available as an immunosuppressant for transplant patients so it its commercially available but it’s a stretch I’m not willing to make to take it now for possible health benefits.

Ok, How about spermadin ? These are crystals found in sperm , oddly enough by the inventor of the microscope Antoine Van Leeuwenhoek, and it stimulates autophagy and stabilizes the epigenome…1.2 grams a day improved memory in one trial…you can get it in wheat germ if you like.

What about metformin? This is an AMPK activator drug which is used worldwide for diabetes. Its so safe that in half the world its available over the counter. The drug lowers ATP and produces an increase in mitochondria….its an mTOR inhibitor and raises NAD levels so what’s not to like? Well it’s still artificial and I would like to age as naturally as possible but I am looking forward to better studies and certainly respect people who want to try these compounds.

Which leads us to Berberine which is a plant molecule similar to metformin…it can mimic metformin…it reduces chemical reactions in the body and the body responds by making more energy and mitochondria. You have to use 1-2 grams a day. I plan to try the Berberine for a month and see if it improves any metrics of my health and see how I feel but I will hold off on the others until I see more study results. I am sure there are many more compounds I have left out but that leaves fodder for another column. Until then ….work on the basics of diet and exercise….don’t expect any supplement to be as beneficial as eating health and getting a workout. You know the drill but have to find the motivation to do it. Someone once said change comes from inspiration or desperation ….which will it be for you? Until next month Get Well and Stay Well

JT BARRY MD

FEBRUARY 2022 TABLE HOPPING ARTICLE

FRUIT ISN’T ALL THAT !

This article draws heavily from great work on carbohydrate metabolism by Dr Gary Fettke, a Tazmanian surgeon who drew the ire of the nutritional service at his hospitals when he suggested diabetic patients could prevent further amputations if they lowered their carbohydrate intake. Even though the government guidelines suggest you should get half your calories from fruits and grains, excessive carbohydrate intake is dangerous. For millenium carbohydrate intake was seasonal and fruit based and since we began to bake and use grains our health has deteriorated. Fruit was intended to fatten us up for Winter. We now have endless Summer in our groceries so we are not seasonal anymore and it shows in our waistlines.

All carbohydrates are sugar…There are many different sugars ..glucose, sucrose, fructose for example. The human body goes to great lengths to remove excess sugar from the bloodstream. Any excess sugar in the bloodstream is dealt with aggressively by the body to keep the levels low because too much is toxic. Turns out more than a teaspoon of sugar has a toxic effect

It’s all about energy production and that brings up the Krebs cycle in which acetyl coA is converted by the mitochondria into energy….ATP to be exact. ..Acetyl coA can be produced from fatty acids, sugar and amino acids. There is no absolute need for sugar as an energy source in contrast to fatty acids and amino acids which are absolutely essential. Glucose can be consumed by us or created by gluconeogenesis and from glycogen stores. Excess glucose triggers an elevation of sugar which in turn stimulates insulin. More than one teaspoon calls for a response. A slice of bread contains 5 teaspoons of sugar so that’s a lot of extra sugar that the body has to remove from circulation. .Glucose and fructose are very similar sugars but are handled very differently by the body. Fruits contain both glucose and fructose in roughly even proportions.

Chronic elevation of sugar causes advanced glycogenated end products to build up. This in turns oxidized fats etc to contribute to inflammation. These AGE’s affect the brain, the eyes, the heart, the kidneys, wound healing , infection and cancer. Elevated glucose levels also glycate other tissues and lipids. The glycocalyx is a coating of every endothelial blood vessel….its critical to health and is fragile …this organ of sorts is particularly affected by elevated blood glucose. Damaging the glycocalyx is analogous to damaging the lining of your gut causing leaky blood vessels much as you get a leaky gut.

Excess sugar triggers increased insulin which is generally inflammatory. There is a direct correlation between insulin levels and degree of inflammatory markers in the knee as shown in a study done within the last 5 years and mentioned by Dr Fettke. Insulin reduces vitamin D absorption, Insulin stimulates tumor growth; Insulin lowers magnesium levels which are required in myriad biochemical pathways and insulin increases clotting measures.

Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC

Now Fructose in particular is mostly metabolized in the liver… Fructose raises uric acid which is also inflammatory and elevated uric acid negatively affects the production of nitric acid which is a critical component of vascular heath. Uric acid decreases white cell function and adversely affects our response to infection. Fructose actually increases hunger via both the leptin and ghrelin pathways if you want to get technical. Fructose increases the oxidation of ldl…the type of lipid your doctor calls the “ the bad cholesterol “

Just as an aside…why do they give you so much sugar in the hospital? . It’s not just in the food…breakfast pizza and pecan pie are touted as healthy…Sugar is directly toxic to the immune system but how many people are getting a sugar water Intravenous solution.?! One more thing to worry about when you go into the hospital.

One way to manage your sugars is obviously via your diet. Keto diets are low carbohydrate/ low sugar diets that directly address this issue of carbohydrate toxicity. Many physicians are leery of a keto diet but let’s look at the keto diet in the most vulnerable population we have…..unborn babies. We have a long and consistent medical record here. Mothers with morning sickness are often in ketosis…this is something we have seen and measured . The other end of the spectrum is babies whose mothers have gestational diabetes. So. Some babies are exposed to very low sugar and some babies are exposed to high sugar levels and we can track their outcomes. . It’s no surprise that the keto exposed babies are healthier in every metric compared to the gestational diabetes babies….premature births, birth defects etc all worse in the high sugar good.

Scheduled obesity is the process of turning sugar into fat during times of plenty. There were papers published as early as 1948 that connected sugar with illness. By 1992 the food guide suggested 5-9 fruits and vegetables a day but there is no real science behind that recommendation. In 2005 the CDC partnered with the produce industry to continue to promote fruits along with vegetables. The Epic Study in Europe involved over 500,000 people and lasted for over 15 years and did not show a correlation between fruits and veggies and cancer rate.

How much sugar is healthy according to the World Health Organization? ….25 grams which is 6 teaspoons of sugar a day. We have gone from 5 pounds a year of sugar consumption to 152 pounds a year. And that’s an average.

Well, what about all the other nutritional benefits of fruit in terms of minerals, vitamins and micronutrients. ? Fruit nutritional value is overstated. Look at antioxidants….a cup of coffee has much more antioxidants than most fruits/ Look at vitamins …..well green leafy veggies have much more vitamin E, vitamin A etc. Look at minerals….again green leafy veggies ie spinach has more potassium than the banana Fruit also has less phytonutrients and fiber than many vegetables.

So let’s start the New Year off right and keep things in perspective. Fruit may not be the substance you should base your diet on but it’s way healthier than any fast food, fried food , processed food and liquid calories like soda and fruit drinks. Have fruit but seasonally and sporadically like your ancestors experienced and see how you feel. If you want to try to lower your carbohydrates in your diet I would refer you to Keto Syracuse on facebook. Keto Phil knows what he is talking about and has all the references you would ever want and more.

Knowledge is power . Make this the year you become truly powerful.! Until next month….get well and stay well.

JT BARRY MD

JANUARY 2022 TABLEHOPPING ARTICLE

You’re going to have to blame this article on my sister Brenda because, I’ve been warned previously, to avoid vaccine discussions as no one in the health department at the CDC or the FDA at cetera wants to hear any dissenting views on the safety and efficacy of the vaccine. But, when my sister ,a board-certified gynecologist, mentioned that she hoped people like Dr. Mercola would be sanctioned for spreading untruths about the vaccine. I just had to take issue with her. Show me one discrepancy, one untruth the doctor Mercola has said and I will cease bombarding you with article after article about the vaccines and their serious lack of efficacy and even more serious safety. So far the bombardment has continued unabate.

First off, it is TRUE that the very definition of vaccine had to be changed to allow these new modalities to be called vaccines. It’s very important to someone that they be called vaccines rather than experimental delivery systems because the bulk of the public believes in the long and safe history of vaccination. Don’t take my word for it… Compare the 2013 definition of vaccine with the 2021 definition in Marriam Webster.. Is it nitpicking? Do words matter?

Secondly, can we look to the global reality for a moment? Sweden did the least in response to the COVID and has been affected the least. Very low death rates, Very low hospitalization rates, when compared to many many countries with very restrictive rules and very aggressive vaccine mandates. Find out which countries are doing the best in any arena and do what they do… that seems like a reasonable approach which our health agencies completely ignore.

The mantra, the credo, the remonstration from on high is Get the shot or you are not intelligent. Get the shot or you will kill grandma. Get the shot or you are not patriotic. Get the shot to protect others. If it’s so safe and effective why are they bribing people and shaming people into getting the shot. Although they admit they don’t have accurate data…. CDC director Rochelle Walensky ,Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, and Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research all testified before Congress admitting that probably 40% of their staff have not been vaccinated. If these vaccines are saving the world why isn’t there 100% compliance from the people who study them? Isn’t that a fair question?

Why didn’t this next story make every headline in every news channel in the world ? In response to a request for a complete copy of the all important Pfizer study ( upon which our entire government response relies) the FDA has petitioned the courts ( we paid for it and have to sue the FDA for access.. really??) to allow them until 2076…thats 55 years from now. If this is the most important vaccine of all time then free and clear and immediate access to the data should be a foregone conclusion. This should all be on a PDF that anyone and everyone can download. We paid for the trials. We paid for the vaccines. There is no rational reason this data needs 55 years to release. As the Attorneys for the researchers trying to get access to the data pointed out….They took 108 days for the FDA to carry out a very thorough and complete analysis of the vaccine trial. . It shouldn’t take longer than that to release the data. Sorry but it Just makes me think they are hiding something. Could it be safety data ? Could it be efficacy data? And just as importantly this story of government agency mismanagement and delay is buried. Don’t believe me..”.type 55 years to release Pfizer data “ on your search bar.

So let’s get to the heart of the matter. Safety and Efficacy.

My training has involved using the Number Needed to Treat as a marker of efficacy. This translates into how many people have to receive treatment for one person to benefit. Usually if the NNT is greater than 50 it’s considered a low benefit intervention. According to the Lancet the number needed to vaccinate is 81 for the Moderna–NIH, 78 for the AstraZeneca–Oxford,, 84 for the J&J, and 119 for the Pfizer–BioNTech vaccines. Those numbers are to prevent one infection. To prevent one serious complication or one death the number needed to vaccinate is between 16,000 and 100,000. That’s a lot of shots to prevent one death but would be worth it as long as there are no safety concerns.

You hear all the time that vaccines have a greater than 90% efficacy. But that’s relative risk which looks impressive…if you use absolute risk it looks quite differently. From an article published in the NIH National Library of Medicine “The absence of reported absolute risk reduction in COVID-19 vaccine clinical trials can lead to outcome reporting bias that affects the interpretation of vaccine efficacy.Unreported absolute risk reduction measures of 0.7% and 1.1% for the Pfzier/BioNTech and Moderna vaccines, respectively, are very much lower than the reported relative risk reduction measures. Reporting absolute risk reduction measures is essential to prevent outcome reporting bias in evaluation of COVID-19 vaccine efficacy.” Here is the reference PMID: 33652582. It’s pretty clear from a series of trials that the vaccine can cut down the risk of infection for a few months but it’s also very clear that the protection wanes over just a few months. From a personal standpoint most of the patients I am treating now have been vaccinated. Our health department has the data about the number of vaccinated and unvaccinated in the hospitals or the number of people who have died from covid who have been vaccinated or not vaccinated. They chose not to report them. The National Health Service in Great Britain does release this data and it clearly shows no difference in death rates between the vaccinated and unvaccinated. The Pfizer trial actually had more deaths in the treatment group than the placebo. The extra deaths were primarily due to heart related issues and were not considered related to the vaccine.

As commented on the NNT website “ In the end, we feel it is an embarrassing dereliction that vaccine trials performed in the shadow of the worst pandemic in a century have not produced answers to the world’s most pressing questions. That is a product of trial design and data transparency. These two matters were left, inexplicably, to the discretion of drug makers”. The absolute number of deaths in the Pfizer ;trial attributed to covid were one in the vaccine group and two in the placebo group so there was one less death out of 20,000 people which hardly seems big enough effect to justify mandating this shot to everyone. .

On to safety….the official line is the vaccines are safe but the government controlled and sponsored site that reports on these issues… the Vaccine Adverse Event Reporting Site VAERS..has listed over 850,000 adverse events and over 18,000 deaths attributed to the vaccine. Now multiple studies have shown that these events are grossly underreported and that the actual numbers are 10 times to 40 times what’s listed in the VAERS. Toby Rogers put together this list of people who have looked at this issue…”Director David Kessler in an article in the Journal of the American Medical Association stated that “only about 1% of serious events are reported to the FDA.” A report for the U.S. Department of Health and Human Services by Harvard Pilgrim Healthcare Inc. confirmed that VAERS undercounts actual vaccine injuries by a factor of 100.

More recently several scholars have attempted to refine these initial estimates.Kirsch, Rose, and Crawford estimate that VAERS undercounts fatal vaccine reactions by a factor of 41.Dr. Jessica Rose, a statistician in Israel, recently calculated an under-reporting factor of 31 for all severe adverse events following vaccination.

So, if 18,000 deaths have been reported, what’s the real number…180,000 or was it 700,000. Either way ….these vaccines are not as safe as they have been touted.

As I write this Dr Gundry of the Plant Paradox fame, a cardiac surgeon who now focuses on holistic medicine and who has a very vested interest in avoiding controversy has submitted an abstract to Circulation documenting his findings that covid vaccines DOUBLE the heart attack markers he measures on all patients. He wasn’t looking for this.. he was just following the same data on all his patients and noticed this obvious change in the inflammatory markers that affect heart attack risk. Maybe those ‘unrelated “ heart attacks in the Pfizer trial were not unrelated at all. https://www.ahajournals.org/doi/10.1161/circ.144.suppl_1.10712

Since it’s pretty evident that the vaccines don’t prevent infection or transmission but they at least prevent hospitalizations and death so it’s worth it. Unfortunately the most recent data from Europe (where they report vaccinated and unvaccinated data ) does not show ANY real reduction in excess mortality in the vaccinated group. Actually in the age group between 16-49 there has been an uptick in excess mortality (not seen at all during the first year of covid) SINCE the introduction of vaccines for that age group. Hospital admission numbers were not routinely reported in the trials for vaccine efficacy so when they say the vaccine prevents severe disease and death it’s not really based on the trial data.

Speaking of deaths and hospitalizations… in the short, small trial that Pfizer did to get approval of the vaccine in children in the 5-12 age group there was absolutely no difference in the vaccine group or placebo group in terms of serious adverse events. There were ZERO adverse events in either group. So there is no evidence whatsoever that the vaccines prevent serious illness in this group and there is growling evidence that the vaccines can cause serious myocarditis especially in the younger age group. Multiple studies including Dr Toby Rogers have calculated that since children have a very very low risk of serious injury or death, that the vaccines will do more harm than good.

https://tobyrogers.substack.com/p/ten-red-flags-in-the-fdas-risk-benefit. The reference listed is a pretty stunning indictment of the trial.and points out that even though the FDA wants to vaccinate every child regardless of prior infection.. in the study Pfizer excluded children that already had COVID. The CDC has admitted that 40% of children have already had the infection and they want to give all kids the shot even though they have not studied giving the shot to kids that have already had natural immunity.

I have not brought up the infertility issue because we will not have real data here for years. I have not brought up the issue of antibody induced enhancement which was the principal reason prior coronavirus vaccine research had been shut down. The vaccine actually made the animal who received the vaccine much sicker when they were subsequently exposed to the viirus again. That’s right… the vaccine made things worse. Here’s a reference from Nature https://www.nature.com/articles/s41564-020-00789-5. If people who have been vaccinated multiple times start getting sicker… what will they think? Will they clamber for yet another booster.thinking that will help? It will be hard to figure out since we have essentially stopped the control groups ill all the trials done so far. Control groups are vital in any study but apparently not important in the biggest and most important vaccine study in the world.

So, efficacy, limited as it is, is waning. Safety concerns are mounting by the day.. High risk patients should certainly be vaccinated. The rest of us should make our own decisions without the bullying, and mandating that our government seems to be so focused on. You can continue to just follow the sound bites and headlines or you can decide, on this important health issue, to do your own research. Any of the references listed above will start you on your own journey of discovery. Dr Faucci says an attack on him is really an attack on science. I’m saying that science is no monolith and that refusing to acknowledge any problems with the vaccine is not scientific. Until next month….do your own research….get well and stay well.

JT BARRY MD

Don’t Shoot the Messenger

Dr.Mercola

Dr.Mercola

You’re going to have to blame this article on my sister Brenda because, I’ve been warned previously, to avoid vaccine discussions as no one in the health department at the CDC or the FDA at cetera wants to hear any dissenting views on the safety and efficacy of the vaccine. But, when my sister, a boardcertified gynecologist, mentioned that she hoped people like Dr. Mercola would be sanctioned for spreading untruths about the vaccine, I just had to take issue with her. Show me one discrepancy, one untruth the doctor Mercola has said and I will cease bombarding you with article after article about the vaccines and their serious lack of efficacy and even more serious safety. So far the bombardment has continued unabated.

Preventive Medicine Associates, PLLC

First off, it is TRUE that the very definition of vaccine had to be changed to allow these new modalities to be called vaccines. It’s very important to someone that they be called vaccines rather than experimental delivery systems, because the bulk of the public believes in the long and safe history of vaccination. Don’t take my word for it. Compare the 2013 definition of vaccine with the 2021 definition in Marriam Webster. Is it nitpicking? Do words matter? Secondly, can we look to the global reality for a moment? Sweden did the least in response to COVID and has been affected the least. Very low death rates, very low hospitalization rates, when compared to many many countries with very restrictive rules and very aggressive vaccine mandates. Find out which countries are doing the best in any arena and do what they do. That seems like a reasonable approach, which our health agencies completely ignore.

“It is TRUE that the very definition of vaccine had to be changed to allow these new modalities to be called vaccines.”

The mantra, the credo, the remonstration from on high is, Get the shot or you are not intelligent. Get the shot or you will kill grandma. Get the shot or you are not patriotic. Get the shot to protect others. If it’s so safe and effective why are they bribing people and shaming people into getting the shot? Although they admit they don’t have accurate data, CDC director Rochelle Walensky, Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, and Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research all testified before Congress admitting that probably 40% of their staff have not been vaccinated. If these vaccines are saving the world why isn’t there 100% compliance from the people who study them? Isn’t that a fair question?

Preventive Medicine Associates, PLLC

Why didn’t this next story make every headline in every news channel in the world? In response to a request for a complete copy of the all important Pfizer study (upon which our entire government response relies) the FDA has petitioned the courts (we paid for it and have to sue the FDA for access, really??) to allow them until 2076…that’s 55 years from now. If this is the most important vaccine of all time then free and clear and immediate access to the data should be a foregone conclusion. This should all be on a PDF that anyone and everyone can download. We paid for the trials. We paid for the vaccines. There is no rational reason this data needs 55 years to release. As the attorneys for the researchers trying to get access to the data pointed out, they took 108 days for the FDA to carry out a very thorough and complete analysis of the vaccine trial. It shouldn’t take longer than that to release the data. Sorry but it just makes me think they are hiding something. Could it be safety data? Could it be efficacy data? And just as importantly this story of government agency mismanagement and delay is buried. Don’t believe me, type “55 years to release Pfizer data,“ on your search bar.

Preventive Medicine Associates, PLLC

So let’s get to the heart of the matter. Safety and Efficacy. My training has involved using the Number Needed to Treat as a marker of efficacy. This translates into how many people have to receive treatment for one person to benefit. Usually if the NNT is greater than 50 it’s considered a low benefit intervention. According to the Lancet the number needed to vaccinate is 81 for the Moderna–NIH, 78 for the AstraZeneca– Oxford, 84 for the J&J, and 119 for the Pfizer– BioNTech vaccines. Those numbers are to prevent one infection. To prevent one serious complication or one death the number needed to vaccinate is between 16,000 and 100,000. That’s a lot of shots to prevent one death but would be worth it as long as there are no safety concerns.

Preventive Medicine Associates, PLLC

You hear all the time that vaccines have a greater than 90% efficacy. But that’s relative risk which looks impressive, if you use absolute risk it looks quite differently. From an article published in the NIH National Library of Medicine, “The absence of reported absolute risk reduction in COVID-19 vaccine clinical trials can lead to outcome reporting bias that affects the interpretation of vaccine efficacy. Unreported absolute risk reduction measures of 0.7% and 1.1% for the Pfzier/BioNTech and Moderna vaccines, respectively, are very much lower than the reported relative risk reduction measures. Reporting absolute risk reduction measures is essential to prevent outcome reporting bias in evaluation of COVID-19 vaccine efficacy.” Here is the reference PMID: 33652582. It’s pretty clear from a series of trials that the vaccine can cut down the risk of infection for a few months but it’s also very clear that the protection wanes over just a few months. From a personal standpoint most of the patients I am treating now have been vaccinated. Our health department has the data about the number of vaccinated and unvaccinated in the hospitals or the number of people who have died from Covid who have been vaccinated or not vaccinated. They chose not to report them. The National Health Service in Great Britain does release this data and it clearly shows no difference in death rates between the vaccinated and unvaccinated. The Pfizer trial actually had more deaths in the treatment group than the placebo. The extra deaths were primarily due to heart related issues and were not considered related to the vaccine.

“In response to a request for a complete copy of the, all important Pfizer study, the FDA has petitioned the courts (we paid for it and have to sue the FDA for access, really??) to allow them until 2076… that’s 55 years from now.”

As commented on the NNT website, “In the end, we feel it is an embarrassing dereliction that vaccine trials performed in the shadow of the worst pandemic in a century have not produced answers to the world’s most pressing questions. That is a product of trial design and data transparency. These two matters were left, inexplicably, to the discretion of drug makers.”

The absolute number of deaths in the Pfizer trial attributed to Covid were one in the vaccine group and two in the placebo group so there was one less death out of 20,000 people which hardly seems big enough effect to justify mandating this shot to everyone. Onto safety…the official line is the vaccines are safe but the government controlled and sponsored site that reports on these issues, the Vaccine Adverse Event Reporting Site, VAERS, has listed over 850,000 adverse events and over 18,000 deaths attributed to the vaccine. Now multiple studies have shown that these events are grossly underreported and that the actual numbers are 10 times to 40 times what’s listed in the VAERS. Toby Rogers put together this list of people who have looked at this issue. ”Director David Kessler in an article in the Journal of the American Medical Association stated that “only about 1% of serious events are reported to the FDA.” A report for the U.S. Department of Health and Human Services by Harvard Pilgrim Healthcare Inc. confirmed that VAERS undercounts actual vaccine injuries by a factor of 100.

More recently several scholars have attempted to refine these initial estimates. Kirsch, Rose, and Crawford estimate that VAERS undercounts fatal vaccine reactions by a factor of 41. Dr. Jessica Rose, a statistician in Israel, recently calculated an under-reporting factor of 31 for all severe adverse events following vaccination.

So, if 18,000 deaths have been reported, what’s the real number…180,000 or was it 700,000? Either way, these vaccines are not as safe as they have been touted.

As I write this Dr. Gundry of the Plant Paradox fame, a cardiac surgeon who now focuses on holistic medicine and who has a very vested interest in avoiding controversy has submitted an abstract to Circulation documenting his findings that Covid vaccines DOUBLE the heart attack markers he measures on all patients. He wasn’t looking for this…he was just following the same data on all his patients and noticed this obvious change in the inflammatory markers that affect heart attack risk. Maybe those ‘unrelated’ heart attacks in the Pfizer trial were not unrelated at all. https://www.ahajournals.org/doi/10.1161/circ.144. suppl_1.10712

It’s pretty evident that the vaccines don’t prevent infection or transmission, but they at least prevent hospitalizations and death, so it’s worth it. Unfortunately the most recent data from Europe (where they report vaccinated and unvaccinated data) does not show ANY real reduction in excess mortality in the vaccinated group. Actually in the age group between 16-49 there has been an uptick in excess mortality (not seen at all during the first year of Covid) SINCE the introduction of vaccines for that age group. Hospital admission numbers were not routinely reported in the trials for vaccine efficacy so when they say the vaccine prevents severe disease and death it’s not really based on the trial data.

Speaking of deaths and hospitalizations…in the short, small trial that Pfizer did to get approval of the vaccine in children in the 5-12 age group there was absolutely no difference in the vaccine group or placebo group in terms of serious adverse events. There were ZERO adverse events in either group. So there is no evidence whatsoever that the vaccines prevent serious illness in this group and there is growing evidence that the vaccines can cause serious myocarditis especially in the younger age group. Multiple studies including Dr. Toby Rogers have calculated that since children have a very very low risk of serious injury or death, that the vaccines will do more harm than good.

https://tobyrogers.substack.com/p/ten-red-flags-in-the-fdas-risk-benefit. The reference listed is a pretty stunning indictment of the trial, and points out that the FDA wants to vaccinate every child regardless of prior infection. In the study, Pfizer excluded children that already had COVID. The CDC has admitted that 40% of children have already had the infection and they want to give all kids the shot even though they have not studied giving the shot to kids that have already had natural immunity.

I have not brought up the infertility issue because we will not have real data here for years. I have not brought up the issue of antibody induced enhancement which was the principal reason prior coronavirus vaccine research had been shut down. The vaccine actually made the animal who received the vaccine much sicker when they were subsequently exposed to the virus again. That’s right…the vaccine made things worse. Here’s a reference from Nature https://www.nature.com/articles/s41564-020-00789-5. If people who have been vaccinated multiple times start getting sicker…what will they think? Will they clamber for yet another booster, thinking that will help? It will be hard to figure out since we have essentially stopped the control groups on all the trials done so far. Control groups are vital in any study but apparently not important in the biggest and most important vaccine study in the world.

Preventive Medicine Associates, PLLC

So, efficacy, limited as it is, is waning. Safety concerns are mounting by the day. High risk patients should certainly be vaccinated. The rest of us should make our own decisions without the bullying, and mandating that our government seems to be so focused on. You can continue to just follow the sound bites and headlines or you can decide, on this important health issue, to do your own research. Any of the references listed above will start you on your own journey of discovery. Dr Faucci says an attack on him is really an attack on science. I’m saying that science is no monolith and that refusing to acknowledge any problems with the vaccine is not scientific. Until next month…do your own research…get well and stay well.

JT BARRY MD

DECEMBER 2021 TABLEHOPPING ARTICLE

Well, it’s been a long and strange year and we can only hope that next year will restore some normality but I am not holding my breath. Instead let me focus on getting you through the holiday with some healthy advice. No, I am not going to remonstrate you about your eggnog habit or the wassail bowl. Those Xmas cookies and candy studded fruitcakes get a pass in today’s article. I have the whole rest of the year to chide you about your diet. Rather, I am going to give you some gift giving advice.

They have made much in the news about the supply side issues and making sure you can get your presents shipped in time for the holidays.No worries, I have you covered. I always favor the local guy when I can.

Of course you can always start with massage certificates. Either you like massages or you don’t but there are many different types of massage and we have lots of massage therapists in Central New York. Luckily, if you give a person a gift certificate and they are not into massage there is always regifting. If you want to give something a little different why not get a certificate to the Red LIght Spa in Camillus. They offer hot yoga, heat wraps, hot saunas , infrared treatments etc. Surely this is better than another tie or bundt cake. Better to sweat out the toxins than another ugly sweater.

Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC

How about something on the literary side? Dr Gundry’s newest book the Energy Paradox is a great gift for someone who feels run down and worn out. Frankly it’s a great book for anyone who wants to improve their health. Sure , he sells a lot of supplements but that’s absolutely not the focus of the book at all. Dr Chris Knobbe also has a great book entitled Omega 6 Apokalypse that will interest any of your friends who are health conscious. It’s a stunning exploration of the seed oils that are ruining our health one donut, one french fry and one salad dressing at a time.

On a budget? Give the most important thing…the gift of time and companionship.. Take someone for a walk…a tour of the MOLST…. a trip around the Zoo..check out the Christmas tree display at the Everson. Get out with a friend and do something active like snowshoeing at Highland Forest or ice skating downtown. Ok, maybe not take grandma ice skating but you can take the grandkids. How about bringing the family or a friend to the Desantis Holiday Show at St Charles Church Sunday December 12th at 5 pm? This is always a great show for the holidays.

It’s also time to start making your plans for your health next year….if you don’t make plans and have goals you are just drifting through your health care. You are not just some leaf in the gutter swirling around in reaction to the rains..Like it or not your health depends on your diet and environment and you control this. .Make a plan about weight loss, make a plan regarding your exercise, alcohol use, etc. Plan it, track it, change it. It’s great to give gifts to others but what about gifting yourself a plan for better health. Merry Christmas and Happy New Year . Until next year ….get well and stay well….

JT BARRY MD

NOVEMBER 2021 TABLEHOPPING ARTICLE

NEXT GEN

Once again I learn more from my patients than I have from the medical literature. Most of the medical stuff I read in the New England Journal of Medicine, The Green Journal, The Lancet, the Journal of the American Medical Association involves obscure medicines for end stage diseases or political editorials . There is very little in the mainstream medical literature about diet, exercise, sleep and stress. It’s all about chronic disease management not improving health. The phase angle machine that can measure your fat, muscle bone etc as well as provide a measurement of your basic cellular health didnt come from these journals. The alpha stim device which can help anxiety, depression and insomnia didnt come from these journals. Ditto the vitamin scanner and the vascular reactivity test. One of my patients brought me a test that can tell you which metals you are allergic to before you have a joint replacement. Another of my patients keeps challenging me with the energy medicine machines which I thought were a little too new for me until I discovered that NASA uses these machines in all space flights. So too, I discovered the services from RGCC from one of my patients.

Right now, most people go to the cancer doctor and get standard therapies which are based on large clinical trials. We usually treat this cancer with 4 cycles of one combination or other of chemo drugs etc. There is a company called Foundation ONe that will use cell free DNA samples or tissue taken from your cancer to guide the Oncologist in choosing which chemo or therapy to use depending on the bloodwork.. Until now this was the best you could expect. Right now, most people find their cancers either by routine screening i.e. mammograms and colonoscopies or by scans that show tumor growth when the tumor is big enough to be seen. By the time you can see a tumor on a scan we are talking about billions and billions of tumor cells. Until now this was the best you could expect.

Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC

Now, however, there are new kids in town. There are two companies that now offer a chance to have your blood taken and look for cancer cells before it shows up on scans. Although I think it’s very much cancer specific, most experts would say that early detection saves lives. If that’s the case then finding the cancer before it shows up on scans or before it becomes clinically apparent should make a difference. The two companies use different technologies but both say they can detect a variety of cancers from just a sample of your blood. One company is based in America and is called GRAIL and their product is called Galleri . Up to 70% percent of cancer deaths are caused by cancers we don’t have screens for. i.e. pancreatic cancer, ovarian cancer etc. It’s too new to be covered by insurance and, of course, it isn’t perfect but if you test negative it’s very reassuring and if you test positive you can pursue the possible diagnosis. There are 50 different types of cancer this test can detect. There is no perfect test and false positives and negatives occur just as in mammograms and colonoscopies. Of course, these tests do not replace the traditional screens at least for now.

The other company interests me even more. It’s called RGCC and they are out of Greece. They too, offer a blood draw test for cancer but they are not just looking for genetic material that suggests cancer …they are actively looking for cancer cells. Cutting edge tech that has evolved dramatically in recent years is used to isolate any cancer cells and study them This has benefit not only to patients that want to be screened for cancer but for patients who have had cancer in the past and is an independent way to study your cancer cells..Lets say its been 5 years since your breast cancer diagnosis and the doctor says you are disease free …maybe they say you are cured. This blood test will check for the presence of any circulating cancer cells….not just your prior breast cancer but any new or different cancers that may have developed. Then, they give you actionable information about your specific cancer cells…How they react to different chemotherapies as well as how they react to a host of natural substances you might use to augment your treatment like green tea extract or turmeric. This is precision medicine at its best ! The RGCC group also offers cutting edge, personalized, RNA based therapy, not only therapy for cancer but for chronic viral illness and even lyme disease but that’s going to have to wait for another column. The RNA message in the Covid Vaccines turn on protein production and create an immune response. The RNA message in the RGCC injection turns off protein production in the cancer cells, and only the cancer cells, and causes those cancer cells to die.

So, the downside is the cost….Neither test is covered by insurance yet but they are both under a thousand dollars and can buy you a lot of peace of mind. Say your mom and grandmom and sister all had breast cancer….besides just mammos and ultrasounds would you get this test? Your best friend dies of prostate cancer ….you are not curious about you? For you, if it would help you, the future is now…

Until next month….get well and stay well.

Check out the links below and discuss with your healthcare provider.

https://grail.com/clinical-expertise/
https://www.rgcc-group.com/

JT BARRY MD

OCTOBER TABLE HOPPING 2021

YOUR DOCTOR SAYS YOU CAN’T PREVENT OR TREAT DEMENTIA ARE THEY WRONG ON BOTH COUNTS??

I have been reviewing Dr Chris Knobe’s excellent work on the dangers of the seed oils, the omega 6 oils as inflammatory and related to most modern diseases. The oils, canola, corn oil, sunflower oil etc are polyunsaturated and therefore highly likely to oxidize which is a chemical change in their makeup that makes them antinutritious. Or you could equally call it slow food poisoning because this stuff is ineverything processed. Excess Omega 6 , and by that I mean the Standard American DIet, is dementogenic, atherogenic, obesogenic, carcinogenic , carcinogenic….I mean come on people how many “genics” do you have to hear before you get the idea these are man made chemicals that don’t belong in your body and are sabotaging your health.

Then I was listening to the Rhonda Patrick Found my Fitness Podcast with Dr William Harris who has worked his entire career investigating Omega 3 oils which are thought to be anti-inflammatory. The higher your Omega 3 index is the better your overall health and the lower your mortality. This is something you can easily measure at your doctor’s office and treat at your grocery store.

Then, to really hammer it home comes the recent Youtube videos of Dr Paul Mason who has posted lectures again linking dementia to your diet. Once you whet your appetite with the short video linked here you can refer to his other work.

In this video posted in September he reviews the literature and confirms that dementia is a dietary issue…not a genetic one. Sure there are genetic risk factors that can affect your risk but they seem to do so only in the presence of an inflammatory diet. Dr Mason reviewed the famous Nigerian study where people who have the highest possible genetic risk still have very low rates of dementia unless and until they adopt the Western diet. …watch the great dr paul; mason reversing .look at the nigerian study…proves its not genetic…didn’t have dementia 100 years ago and our genes have not changed in that short a time…seed oils and fructose….table sugar is 50% fructose….causes insulin resistance…after nine days you can reserve the liver.

There were only rare cases of dementia diagnosed 100 years ago and dementia is rampant now and our genes have not changed over 100 years…genetics takes hundreds of generations. What I liked about this video was the inclusion of the damage done by fructose and how this makes oxidation worse. So you have the one – two punch of insulin resistance / diabetes (which affects most of us if you do the right test) and the damaged and damaging seed oils which acts as a double whammy. I had not previously seen evidence that diabetics actually absorb more of the oxidized oils than non diabetics…makes sense when you think of the damaged gut lining. Also his finding that the highest risk allele the apoe4 ( the gene variants that affect your risk factor for dementia) is the highest risk because it’s the most susceptible to oxidation (from the seed oils) and glycation (damage from the high insulin/ fructose) was new to me and makes sense and might even be true.

What’s that Mr. It won’t happen to me!? Well , currently the risk of dementia doubles every 5 years starting after age 65. 43% of people over 85 carry the diagnosis and we haven’t really come up with an effective treatment since it was first diagnosed in 1906 despite spendin billions and billions of dollars and over 200 failed trials.

What’s that Mr So there’s nothing to be done about it? Well there is if you look at things from a metabolic angle. The brain has 2 percent of total body volume but uses 20% of metabolic energy. The brain is a stove ! And by using sugar as a fuel you are gunking up the pipes . By using ketones as fuel you clean out the pipes and burn more evenly. Ketones can allow the brain of demented patients to use a new stable healthy reliable food soursce as glucose is no longer able lto be used as fuel djue to insulin resistnace. High sugar levels are not good for the brain long term.

Diabetics are two to five times more likely to get demented..the bigger the belly the bigger the risk of dementia..triple the risk compared to slim people.There have been 31 trials comparing low-carbohydrate and low-fat diets that reached statistical significant results every single one of them showed better weight loss with a low carb diet.

Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC

Certain cells of the brain can take up sugar without any help but other cells which are spread throughout the brain but interestingly are concentrated in the hippocampus. This is a major memory area. These cells need insulin in order to get the sugar in the brain and if you have insulin resistance you’re not getting adequate sugar to these cells. These cells can however use ketones without any difficulty whatsoever.

People talk about amyloid plaques in the brain being associated with dementia . Actually the amyloid monomer is at very protective of the brain it’s when they are clumped together that it becomes pathologic but the amyloid itself is normally produced by the brain and has protective effect Studies have shown that HDL, that’s right the components of the lipid panel that your doctor has ordered for you many times, actually has protective effect on the brain trying to clear it of these amyloid products . That gets back to the Apoe4 allele…these genetic variants affect the hdl ..damaged hdl can’t clear plaque as well hence their increased risk of dementia. And oxidation ( damage from seed or plant oils) and glycation (damage from higher fructose and high fructose corn syrup/diabetes etc ) are what affects the HDL particles.One study showed that HDL levels over 55 offers a 50% protection of Alzheimer’s. It’s possible that the higher your HDL the less likely you are to have Alzheimer’s Looking at this from the angle of reducing dementia risk we have to mention sleep as well. Sleep deprivation increases beta-amyloid deposition so deprivation equals deposition equals dementia. And this has been shown to happen after only one night of poor sleep based on the Dr Mason data. Sleep deprivation worsens insulin resistance and that’s a consistent if not unifying theme. Check your continuous glucose monitor, your normal morning insulin spike will be higher in the mornings after poor sleep.

Interestingly the dietary supplement carnosine has been shown to both to lower insulin resistance and to prevent glycosylation . Carnosine comes only from flesh that is meat ,it’s not found in plants and Doctor Paul Mason points out that this lack of carnosine might increase the risk of dementia in vegetarians. I am not suggesting you start popping carnosine…do your own research . I haven’t taken it …yet….but it’s intriguing.

Bottom line is an ancestral diet of unprocessed food is your best bet to optimum health. Check out the Weston Price Foundation. https://www.westonaprice.org/ .Of course the most comprehensive approach to dementia I think is the Dr Dale Breseden approach which you can look up as well and a local resource for real evaluation and treatment is right here in town at Clarity Clinical Research . I have not become an official Dale Breseden but I am looking into it bacause I dont see other people locally doing it.

J T BARRY MD

SEPTEMBER 2021 TABLEHOPPING

I have two interesting things for you this month..both can be very helpful regarding your health and both are widely available and both are free ! How often does a doctor say that ! I am always on the outlook for tools and techniques that can improve your health and you need look no further than your smartphone.

First up is an app for those of you who want to try intermittent fasting and need a little motivation or advice. The app is called Zero…..its produced by Dr Peter Atia who has made healthgevity his lifelong mission. This guy has done every conceivable experiment on himself in regards to exercise, diet, supplements etc and has produced this app to help with what he ( and most people in the health improvement arena) thinks in an effective and important strategy to improve your health. He is a big Insulin guy as well. As I have written previously, keeping your insulin low is important to keep your inflammation low and Intermittent Fasting is one way to do that. Most of us eat from the time we get up until we tuck ourselves in at night and that’s a lot of work for your pancreas. If you can limit the time frame in which you eat to 8 hours or less that can help lower your overall insulin and improve your health. Of course, the most restrictive time frame besides completely fasting is a 2 hour window. This is the one meal a day model which studies have shown is very healthy and results in very low insulin and inflammatory markers but most of us don’t have the fortitude for that. My suggestion is to skip breakfast…(dont break fast) and eat between noon and 8 pm. Work your way towards that and use the Zero app to keep yourself honest and answer questions like taking supplements when you are fasting etc. There is a premium version of the app but you can get plenty of milage with the free version. Peter Atia is all over podcast and Youtube so you can see for yourself the guy behind the app. Also for more on intermittent fasting and insulin etc I refer you to the great Dr Jason Fung who you can youtube (Did I just use a noun as a verb? ) While you are at it, ask your doctor to check your fasting insulin level. It’s very simple…the lower your fasting insulin the overall healthier you are. And visa versa. It’s a cheap, simple , independent test of your health and you should ask for it. Your doctor has been trained to check your glucose but your insulin level will reveal your metabolic status years and years before you would otherwise be considered a diabetic. Don’t take my word for it, ask Drs Gundry, Mercola, Attia, Saladino, Knobbe, Gregor, etc…these doctors may have very different opinions on the best diet to improve your health but they universally believe that a low insulin level is desirable.

Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC

Now the second app is really a series of apps and again it’s oriented towards trying to help you with your resolve and motivation. You don’t lose weight because you should , or could you lose weight when you must. As Tony Robbins says you meet your musts. I could, I should, I think …those are not change words…I must, I will, …those are change words. But the apps are not about changing words, they are about changing your focus and attention. These apps, which are also free at the app stores, work via hypnosis. You can get hypnosis apps for weight loss , for drinking issues, to improve sleep etc. Before you start fumfering around that you can’t be hypnotized, let’s look at how well you are doing with your bad habits on your own. Most of us need help changing habits…You can join a group, zoom, or journal , but what’s really important is changing your motivation and outlook and that’s where hypnosis comes in.

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Hypnosis is a state of relaxation with heightened and focused attention. It was first made popular by a German physician named Franz Mesmer who invoked the concept of animal magnetism. Later, a British physician named James Braid coined the term hypnosis from the Greek god of sleep hypnos. None less than Sigmund Frued took it up but later abandoned its use in favor of free association techniques he later championed. I am not talking about stage hypnosis. I am talking about one on one sessions with a trained practitioner to see if you can work on a particular problem. That’s what I have always recommended to my patients having trouble with making progress on a particular health problem. We have several well established hypnosis practices in the Central New York area.

Now, however, as apparently everything will be, it’s available on the smartphone. Why not give one of the many apps a try and see what happens. I have personally seen the effects of hypnosis and the literature is full of support for this modality. If the app helps but not enough , then perhaps, seek out an in person experience with a qualified professional.

Take control of your health. Take control of your behavior. Change your health destiny.

Until next month….get well …stay well

J T BARRY MD

AUGUST 2021 TABLEHOPPING

 Preventive Medicine Associates, PLLCOne thing I notice as people are out and about more but honestly I see every day in my office is that people slouch. Yes you…you slouch a lot. Your posture sucks and it’s possibly affecting your health. Your mother was right again. Posture affects more than just how tall you appear. Poor posture can create a host of symptoms from back pain, headache, fatigue, breathing problems, jaw pain and even knee hip and foot pain at least according to the Cleveland Clinic. According to the American Posture Institute bad posture is a major risk factor for falls in the elderly and since falls in the elderly are a major risk factor for death ….poor posture = increased mortality. So it’s not just about how you look ..it’s about your whole body health. Most of the articles about posture on the internet are oriented around gaining height but my concern with your slouching is that it contributes to your poor health. I am a primary care physician not a chiropractor but both professions can agree that posture is important and working on your posture can have real benefits. So, your posture is bad but your grandkids posture is even worse since they are always looking down at their cellphones and there’s little chance of that changing.

Here’s a simple test from the Mayo Clinic to check your posture…it’s called the wall test.

Stand so that the back of your head, your shoulder blades and your buttoc ks touch the wall, and your heels are 2 to 4 inches from the wall. Put a flat hand behind the small of your back. You should be able to just barely slide your hand between your lower back and the wall for a correct lower back curve. If there’s too much space behind your lower back, draw your belly button toward your spine. This flattens the curve in your back and gently brings your lower back closer to the wall. If there’s too little space behind your lower back, arch your back just enough so that your hand can slide behind you. Walk away from the wall while holding a proper posture. Then return to the wall to check whether you kept a correct posture.

There are lots of options to help you work on your posture including some devices which buzz like the Upright Go and the Uposture which signal you if there is a change in posture ….I have no experience with them and just ordered the Uposture to check it out. I often recommend to my patients that they consider a garment to help their posture….they are called posture guards. I can’t recommend any of them in particular but they are not expensive and you can get a good sense of what they look like on the internet. You can also go to physical therapy and work on your posture and sometimes they use flexible tape that acts like the garments and helps maintain posture. There is a school of posture called the Alexander Technique and we have a local expert in this technique..Kathryn M Miranda….who has taught this program for decades. She can be reached at 315-412-4829.

I don’t think any of us are usually aware of our posture unless someone points it out …that’s why I like the garment idea …it’s a constant reminder to straighten up and fly right. I too am working on my posture…my wife and I are taking dance lessons in preparation for my daughter’s upcoming wedding and posture is the first thing the dance instructor focused on. Well, that’s what the second dance instructor focused on anyway…the first dance instructor fired us….That must tell you something right there…..I have discovered I like taking dance lessons. My wife and I have been married over 30 years and I worry that things could get a little stale and dancing once a week together really gives us something to do that focuses on both of us. Thankfully she seems to enjoy it as much as I do. If you are in a relationship that in any way could benefit from something new in your life I highly recommend giving dance lessons a try. Our instructor is suffering enough…go find your own and …work on your dance steps and your posture at the same time.

JT BARRY MD

JULY 2021 TABLEHOPPING

THE ENERGY PARADOX

I will get to Magnesium in my next article but I just read Dr Gundry’s The Energy Paradox and wanted to bring it to your attention. His earlier works including the Plant Paradox radically changed my approach to illness and wellness and since so many people suffer from a lack of energy I thought you should know about it. I also highly recommend Walking with Peetey the dog who saved my life but that’s another article entirely.That book too brings together many of the concepts I bring up in the office everyday but again …another day.

The Energy Paradox addresses the issue around fatigue….When your get up and go has gotten up and gone. Many people erroneously believe that you run out of energy as you age but Dr Gundry points out that you are just running out of the right fuel ..that you are not recharging your body’s power and battery pack …your mitochondria. Mitochondria are tiny organelles that are found in almost every cell in your body and produce the vast percentage of all the energy your body manufactures in a day. If your mitochondria are happy …you are healthy. If they are not…you are not. Furthermore the mitochondria are heavily influenced by the bugs in your gut …there’s that microbiome connection again ! The mitochondria need full spectrum light ( which controls energy production via quantum mechanics..read the book for details ), properly constructed cell membranes (which brings us back to the omega 3 / 6 ratio I preach about and which your doctor can easily test for) and interestingly enough melatonin. Yes , it turns out the sleep inducing chemical produced by your pineal gland is a major protector of mitochondrial function. You don’t have to depend on just your own production of melatonin…it’s found in abundance in certain foods like olives, olive oil,pistachios and mushrooms. Dr Gundry posits that it’s not the resveratrol in red wine that makes it so healthy, it’s the melatonin !

Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC
Preventive Medicine Associates, PLLC

The standard american diet overwhelms your mitochondria, damages your gut lining, changes the character of the microbiome in your gut and the processed foods damage energy production so it’s no wonder you lack the energy of youth. Furthermore , as Dr Gundry points out, our eating habits overwhelm the gut and the mitochondria by presenting too many nutrients too often that the mitochondria shut down to protect themselves. When the mitochondria are damaged it TAKES energy to destroy them and activates the immune system. The restorative medicine field has long held that all disease is inflammation and all disease is mitochondrial dysfunction and all disease begins in the gut and now you begin to see the interconnectivity of these theories. Dr Gundry’s research takes a whole different approach to the benefits of the keto diet. I thought the keto diet produced ketones which are a clean fuel for your cells and mitochondria. He postulates that these ketones and butyrates are actually communicating to your cells that times are hard and the mitochondria have to be more efficient and more plentiful in response to this stress.

How to improve your mitochondrial function and thereby improve your energy production? Get exposed to light…get outdoors. Dramatically cut down on the linoleic acid in your diet ( canola oil and the other seed oils) while adding Omega 3’s like fish, fish oil etc. He has long recommended Olive oil but now adds sesame oil as an oil that is a powerful antioxidant, a blocker of inflammation at the gut wall level and even has a protective effect against electromagnetic fields! Do some strength training or resistance work which increases the number of mitochondria in your cells. Change the composition of the bugs in your gut and the signals they send your cells and mitochondria by eating more fiber ( the term he uses to describe these substances that are made by the bacteria which then communicate with our bodies is post biotics).

Finally he again promotes the concept of time limited eating. Not grazing from sunup to sundown and beyond as most Americans do but limiting the time you consume food so the mitochondria are not overworked and have some down time to rest and repair. I am not going to get into the details about his dietary recommendations , his suggested supplements and his list of medications and chemicals to avoid. That’s too much for one or two columns to give justice to. This book is packed with details, loaded with references and pretty easy to read. If you want to change your energy level, lower your inflammation, and raise your overall health you want to read this book. Do yourself and your mitochondria a favor and read this book. You don’t have to get any special lab tests done to see results. You don’t have to read any testimonials. You will feel the results for yourself. This is called a N of 1 trial. You be the judge. Until next month…get well…stay well….

JT BARRY MD